Principlev1
Run experiments sequentially when they share outcome
Run experiments sequentially when they share outcome variables or operate through overlapping mechanisms; run them in parallel only when they are independent on outcome, mechanism, and temporal dimensions.
Why This Is a Principle
This derives from Patterns Exist in Hierarchical Logical Levels (patterns exist in hierarchical levels) and The behavior of a system arises from its structure, not from (system behavior arises from structure). The principle prescribes a decision rule for experimental scheduling that follows from the axiom that confounding occurs through shared structures. It's actionable and domain-general.